Read this first: supplements are not medicines
Dietary supplements are not medicines. In the United States they are regulated as food rather than drugs, which means the FDA does not review them for safety or effectiveness before they go on sale, and manufacturers cannot legally claim a supplement treats, cures, or prevents any disease. Nothing on this page is a substitute for prescription treatment, and no supplement described here has been shown to produce the weight loss seen with semaglutide or tirzepatide. If you are considering a supplement — particularly alongside prescription medication — talk to a doctor or pharmacist first, because interactions are real and some ingredients are not appropriate for everyone.
GLP-1 Probiotic+ at a Glance
- Brand
- Codeage
- Format
- 90 vegetable capsules
- What it is
- The broadest ingredient list here, at the lowest price — with the trade-offs that implies
- Intended use
- A daily dietary supplement marketed for metabolic and GLP-1 support. Not a medication.
- Pricing
- Around $29.99 for 90 vegetable capsules
- Last reviewed
- August 5, 2026
Product Overview
Codeage takes the opposite approach to Pendulum. Where Pendulum narrows to a few strains and publishes counts, Codeage assembles a long ingredient list spanning botanicals, minerals, and probiotics in one capsule.
The formula includes chromium, berberine HCl, decaffeinated green tea extract standardised to 50% EGCG, gymnema sylvestre, and curcumin standardised to 95% curcuminoids, alongside probiotic content.
At around $29.99 for 90 capsules it is by far the cheapest option here. Codeage also sells related SKUs including GLP-Advantage+ (curcumin, L-taurine, trans-resveratrol) and GLP-Harmony Companion+ (lion's mane, PEA, colostrum, shilajit, elder fruit, akkermansia, resveratrol) at Target.
The problem with long ingredient lists is dosing. Fitting a dozen actives into a capsule usually means each is present below the dose used in research — berberine research typically uses 900–2,000 mg per day, which alone would fill several capsules.
Manufacturer
Codeage, a US supplement brand sold direct and through retailers including Amazon, Target, and Vitacost.
Ingredients and Amounts
| Ingredient | Published amount | Notes |
|---|---|---|
| Berberine HCl | Per-capsule amount not published in the sources we reviewed | Research doses are typically 900–2,000 mg/day in divided doses |
| Chromium | Amount not published in the sources we reviewed | A trace mineral studied for glucose metabolism |
| Decaffeinated green tea extract (50% EGCG) | Amount not published in the sources we reviewed | Standardised extract |
| Gymnema sylvestre | Amount not published in the sources we reviewed | A botanical traditionally used for sweet-taste suppression |
| Curcumin (95% curcuminoids) | Amount not published in the sources we reviewed | Standardised turmeric extract |
| Probiotic content | CFU counts not published in the sources we reviewed | — |
Other ingredients: Hypromellose (vegetarian capsule), microcrystalline cellulose, silica.
What the Manufacturer Says
These are the manufacturer's own marketing claims, reproduced so you can compare them against the evidence in the next two sections. Listing them is not endorsing them.
- Codeage markets the formula for GLP-1 and metabolic support
- Related SKUs are marketed as "GLP-1 agonist support," language that invites a comparison to prescription medication
- Products carry the standard FDA disclaimer
What the Evidence Actually Shows
Available scientific support
- Several individual ingredients have genuine research: berberine has the most human trial data of any ingredient in this category, and green tea catechins and curcumin have substantial published literature.
- Chromium has been studied for glucose metabolism, with mixed results.
- Gymnema sylvestre has a small evidence base, mostly older and small-scale.
Limitations of that evidence
- The central problem is dose. Berberine research uses 900–2,000 mg/day; you cannot fit that plus a dozen other actives into a capsule at research doses.
- Per-ingredient amounts are not published in the sources we reviewed, so the formula cannot be evaluated against the underlying research at all.
- Curcumin has notoriously poor oral bioavailability without an absorption enhancer, which is not indicated here.
- No published trials of the finished formula.
- Marketing a supplement as "GLP-1 agonist support" is exactly the naming practice public-health researchers have criticised for encouraging consumers to infer medication-like effects.
Directions, Warnings and Allergens
- Directions
- Follow the label directions on the SKU you buy.
- Allergens
- Check the current label for a full allergen statement.
Warnings
- Berberine has meaningful drug interactions, including with metformin and medications metabolised by CYP3A4. Talk to a pharmacist before combining it with prescription medication.
- Berberine should not be used in pregnancy or breastfeeding.
- Green tea extract has been associated with rare cases of liver injury at high doses.
- Consult a healthcare provider before use if you take any prescription medication.
Pricing, Subscription, Refunds and Shipping
Purchase options
- GLP-1 Probiotic+ 90 capsules: $29.99 at Vitacost
- GLP-Advantage+ and GLP-Harmony Companion+ sold separately through Amazon and Target
- Subscription
- Subscription options vary by retailer. Codeage offers subscribe-and-save on its own site.
- Refund policy
- Refund terms depend on where you buy. Retailer policies apply for Amazon, Target, and Vitacost purchases.
- Shipping
- Widely available through major retailers, so shipping follows their standard terms.
Pros and Cons
Pros
- By far the cheapest product in this roundup at around $29.99 for 90 capsules
- Includes berberine, the ingredient with the most human trial data in this category
- Standardised extracts (50% EGCG, 95% curcuminoids) rather than raw powders
- Widely available through major retailers
Cons
- Per-ingredient amounts not published, making the formula impossible to evaluate against research
- Too many actives to plausibly deliver any of them at research doses
- Curcumin without a bioavailability enhancer is poorly absorbed
- "GLP-1 agonist support" branding invites a comparison the evidence does not support
- Berberine carries real drug-interaction risk that a combination product makes easier to overlook
Who It May Be Best For — and Who Should Avoid It
May be best for
- People who want a low-cost entry point and understand the dosing limitations
- Anyone who prefers one capsule over several separate products
Should avoid it
- You take prescription medication without checking berberine interactions first
- You are pregnant or breastfeeding
- You want to know exactly how much of each ingredient you are taking
Alternatives
Frequently Asked Questions
Is Codeage GLP-1 Probiotic+ good value at $29.99?
It is cheap, and it contains ingredients with real research behind them. The difficulty is that the per-ingredient amounts are not published, and the number of actives makes it very unlikely any is present at the dose used in research — berberine trials alone typically use 900–2,000 mg per day. Cheap is not good value if the doses are too low to do anything.
Is berberine in a combination product as good as taking it alone?
Generally no, for dosing reasons. Berberine research uses 900–2,000 mg daily in divided doses, which is a lot of material. A capsule also containing chromium, green tea extract, gymnema, curcumin, and probiotics cannot realistically deliver that. If berberine is what you want, a standalone product at a published dose is the more logical choice — after checking interactions with a pharmacist.
Opens the product page · Verify current pricing and label there
How We Researched This Review
Ingredients, amounts, directions, warnings, and pricing come from the manufacturer's own published label and product pages, or a named retailer, checked on August 5, 2026. Evidence citations point to published research rather than manufacturer marketing. We have not tested this product, and we do not claim to have. Where a manufacturer does not publish something — a CFU count, a refund policy, an allergen statement — this review says so instead of guessing.
Sources
- codeage.com/products/glp-1-probiotic (ingredient list)
- vitacost.com Codeage GLP-1 Probiotic listing (price and other ingredients)
- amazon.com GLP-Advantage+ and target.com GLP-Harmony Companion+ listings (related SKU composition)
Medical Disclaimer
We're not doctors, and this review is for education only — it isn't medical advice. No dietary supplement described here is a treatment for any condition, and none has been shown to produce the weight loss seen with prescription GLP-1 medications. Supplements can interact with prescription drugs. Talk to a doctor or pharmacist before starting anything, especially alongside medication. See our full medical disclaimer.
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