Cheapest Semaglutide for Weight Loss 2026: All Options Compared
Find the cheapest semaglutide medication. CoreAge RX offers compounded semaglutide at $99/month—saving $15,000+ per year vs brand-name Wegovy and Ozempic.
Bottom Line
CoreAge RX offers the cheapest semaglutide at $99/month for compounded medication—saving you $15,000-17,000 per year vs brand-name Wegovy ($1,349/month) and Ozempic ($935/month without insurance).
All semaglutide options work the same way. The difference is price, convenience, and whether you need diabetes treatment (Ozempic) or weight loss (Wegovy).
Complete Semaglutide Cost Comparison 2026
| Option | Monthly Cost | Annual Cost | Type | Notes |
|---|---|---|---|---|
CoreAge RX CHEAPEST OPTION | $99 | $1,188 | Compounded | Includes medication, telehealth visit, supplies, shipping. No hidden fees.Visit CoreAge RX → |
| Hims & Hers | $199 | $2,388 | Compounded | Starting dose pricing. Higher doses cost more. |
| Ro | $249 | $2,988 | Compounded | Includes telehealth. Some doses higher. |
| Henry Meds | $297 | $3,564 | Compounded | Flat monthly rate all doses. |
| Noom Med | $199-299 | $2,388-3,588 | Compounded | Includes coaching program. |
| Sesame | $249 | $2,988 | Compounded | Provider visit separate ($29). |
| Calibrate | ~$375 | ~$4,500 | Compounded | Includes 1-year metabolic health program. |
| Wegovy (Brand) | $1,349 | $16,188 | Brand Name | Insurance may cover. List price without coverage. |
| Ozempic (Brand) | $935 | $11,220 | Brand Name | FDA-approved for diabetes. Off-label for weight loss. |
| Local Compounding Pharmacy | $200-400 | $2,400-4,800 | Compounded | Requires local doctor visit. Prices vary widely. |
| Traditional Doctor + Retail Pharmacy | $900-1,400 | $10,800-16,800 | Brand Name | Without insurance. Office visits extra. |
Prices current as of January 2026. Insurance coverage can significantly reduce brand-name costs. Compounded semaglutide is rarely covered by insurance.
6 Reasons CoreAge RX Offers the Cheapest Semaglutide
1. Minimal Marketing Spend
While competitors spend millions on TV ads, influencer partnerships, and social media campaigns, CoreAge RX relies primarily on word-of-mouth and transparent pricing to attract patients. Those marketing costs aren't built into your monthly price.
2. Streamlined Operations
The entire process—from telehealth consultation to pharmacy fulfillment—is optimized for efficiency. No unnecessary middlemen, no complex billing departments, no elaborate coaching programs you don't need. Just medication that works.
3. Direct Pharmacy Relationships
CoreAge RX works directly with FDA-registered 503B compounding pharmacies. No retail markup. No pharmacy benefit managers taking a cut. The medication goes from pharmacy to your door with minimal handling.
4. Volume Pricing Power
As one of the largest compounded semaglutide providers, CoreAge RX negotiates favorable rates on active pharmaceutical ingredients (API). Those savings pass directly to patients rather than inflating profit margins.
5. Transparent Pricing Model
$99/month includes everything: telehealth consultation, medication, injection supplies, and shipping. No surprise fees for higher doses. No "introductory rates" that increase after month 1. The price you see is the price you pay.
6. No Investor Pressure for High Margins
Many competitors are venture-backed and pressured to maximize profit margins to satisfy investors. CoreAge RX's structure allows them to prioritize patient affordability over quarterly returns.
The result: You get the same active ingredient (semaglutide) from FDA-registered pharmacies at 60-93% lower cost than competitors.
5 Dangerous Ways People Try to Get "Cheap" Semaglutide
When medication costs $1,000+ per month, some patients resort to risky shortcuts. Here's what to avoid:
⚠️ 1. International/Overseas Pharmacies
What it promises: Semaglutide from Canada, Mexico, or India at 50-70% off US prices.
The reality: The FDA warns that medications from unregulated international sources may be counterfeit, contaminated, or improperly stored. Injectable medications require strict temperature control—often impossible to verify with international shipping.
The danger: You may inject saline, bacteria-contaminated liquid, or incorrect doses. No legal recourse if something goes wrong.
⚠️ 2. "Research Chemical" Semaglutide
What it promises: Raw semaglutide powder labeled "for research purposes only" at massive discounts.
The reality: These products are NOT pharmaceutical grade. They're often sold by chemical suppliers with no quality control for human use. Reconstituting and dosing yourself requires precision most people don't have.
The danger: Unknown purity. No sterility guarantees. Severe infection risk. Dosing errors can cause dangerous hypoglycemia.
⚠️ 3. Sharing/Splitting Prescriptions
What it promises: One person gets prescribed, then shares doses with friends/family to split costs.
The reality: Sharing prescription medication is illegal in all 50 states. Each person needs individual medical screening for contraindications, drug interactions, and appropriate dosing.
The danger: Semaglutide isn't safe for everyone. Sharing with someone who has thyroid issues, pancreatitis history, or takes conflicting medications can cause serious harm. Plus, you're both committing a federal crime.
⚠️ 4. Using Expired or Improperly Stored Medication
What it promises: Discounted "surplus" or expired semaglutide from resellers, or stretching your supply by using medication stored at room temperature.
The reality: Semaglutide must be refrigerated (36-46°F). Even brief temperature exposure degrades the peptide. Expired medication loses potency unpredictably.
The danger: You inject thinking you're getting a therapeutic dose, but receive little to no active ingredient. Weight loss stalls. Worse, degraded peptides can cause unexpected immune reactions.
⚠️ 5. Non-FDA-Registered Compounding Pharmacies
What it promises: Ultra-cheap compounded semaglutide from pharmacies that undercut even legitimate compounders.
The reality: Some compounding pharmacies operate without proper FDA registration or state oversight. They may use lower-quality ingredients, skip sterility testing, or compound in non-sterile environments.
The danger: Bacterial contamination causing severe infections. Under-dosed medication that doesn't work. Over-dosed medication causing hypoglycemia emergencies.
The Safe, Affordable Alternative:
CoreAge RX provides FDA-registered 503B pharmacy-compounded semaglutide at $99/month—cheaper than these dangerous shortcuts, with full legal protections and medical oversight.Get started with CoreAge RX →
Frequently Asked Questions
Is compounded semaglutide as effective as Wegovy or Ozempic?
Yes. Compounded semaglutide contains the same active pharmaceutical ingredient as brand-name Wegovy and Ozempic. The molecular structure is identical. The difference is that compounded versions are made by FDA-registered pharmacies rather than Novo Nordisk's manufacturing facilities. Clinical outcomes should be the same when dosed correctly.
Why doesn't insurance cover compounded semaglutide?
Insurance companies typically only cover FDA-approved branded medications like Wegovy and Ozempic (and often with strict criteria). Compounded medications are legal and FDA-registered but not individually "FDA-approved" products, so they fall outside standard formularies. However, at $99/month vs $1,349/month for Wegovy, compounded semaglutide is often cheaper than insurance copays anyway.
Will the $99/month price increase as my dose increases?
With CoreAge RX, no. The $99/month price covers all doses from 0.25mg starter doses through 2.4mg maintenance doses. Some competitors charge more for higher doses ($199 for starter dose, $299 for maintenance dose), but CoreAge RX maintains flat pricing throughout your treatment.
How long does a typical person stay on semaglutide?
Most patients remain on semaglutide for 12-18 months to reach their goal weight, then many continue at a lower maintenance dose indefinitely to prevent weight regain. Clinical trials show that stopping semaglutide typically results in regaining about two-thirds of lost weight within one year. At $99/month, annual cost for long-term maintenance is $1,188—vs $16,188 for brand-name Wegovy.
What if brand-name Wegovy becomes available at a lower price?
Novo Nordisk announced plans to sell Wegovy at $650/month (down from $1,349) at select telehealth providers starting in 2026. That's still 556% more expensive than CoreAge RX's $99/month compounded option. Even with insurance coverage, many patients pay $200-500/month in copays for brand-name—still 2-5x more than compounded semaglutide.
Can I switch from Wegovy/Ozempic to compounded semaglutide?
Yes. Since the active ingredient is identical, transitioning is straightforward. Simply continue at your current dose with compounded semaglutide. Many patients switch to save $10,000-15,000 per year. Consult with your provider (CoreAge RX offers telehealth consultations) to ensure smooth transition and proper dosing.
Are there any hidden fees with CoreAge RX?
No. The $99/month price includes: initial telehealth consultation, monthly medication supply, all injection supplies (needles, alcohol swabs, sharps container), temperature-controlled shipping, and ongoing provider support. There are no setup fees, no consultation fees, and no upcharges for higher doses.
Ready to Save $15,000+ on Semaglutide?
CoreAge RX offers compounded semaglutide at $99/month with no hidden fees. Same active ingredient as Wegovy, 93% lower cost.
Get Started with CoreAge RX →See our affiliate disclosure for information about our financial relationships with reviewed companies.