We tested 14+ telehealth platforms offering semaglutide for weight loss. CoreAge RX ranks #1 for value, transparency, and results at $99/month—saving you $10,000+ per year vs brand-name Wegovy.
After testing 14+ online semaglutide programs, CoreAge RX delivers the best overall value at $99/month with transparent pricing, fast shipping, and comprehensive medical support.
* We may earn a commission. See our affiliate disclosure.
Semaglutide—the active ingredient in Wegovy and Ozempic—has revolutionized weight loss treatment. Clinical trials show it helps people lose 15-17% of their body weight on average, making it one of the most effective medications available for obesity.
But there's a problem: Brand-name Wegovy costs $1,349 per month without insurance, putting it out of reach for most people. Even with insurance, copays often exceed $200-500/month.
The solution? Online telehealth programs offering compounded semaglutide at a fraction of the cost—typically $99-350/month. These programs provide the same active ingredient (semaglutide) through FDA-registered compounding pharmacies, complete with medical oversight and prescription management.
We tested 14+ online semaglutide programs to find which ones offer the best combination of safety, effectiveness, affordability, and customer experience. Here's what we found.
We evaluated each program across 8 key criteria:
Is the total monthly cost clear upfront? Are there hidden fees for consultations, shipping, or supplies?
Does the pharmacy use FDA-registered facilities? Are medications tested for purity and sterility?
Are prescribers licensed physicians or NPs? Can you contact them with questions? How thorough is the intake process?
How responsive is support? Can you reach a human quickly? Do they help with side effects and dosing questions?
How fast is delivery? Is cold-chain shipping included? What happens if medication arrives warm or damaged?
Are needles, alcohol swabs, and sharps containers included? Or do you pay extra for injection supplies?
Can you pause or cancel easily? Are there long-term commitments or cancellation fees?
Considering everything above, do you get what you pay for? Is this a good deal compared to alternatives?
| Rank | Provider | Monthly Cost | Rating | Value Grade |
|---|---|---|---|---|
| 🥇 #1 | CoreAge RX | $99/mo | 9.6/10 | A+ |
| 🥈 #2 | Henry Meds | $297/mo | 8.9/10 | A |
| 🥉 #3 | Ro Body | $145-349/mo | 8.7/10 | B+ |
| #4 | Hims & Hers | $199-349/mo | 8.5/10 | B+ |
| #5 | LifeMD | $249/mo | 8.2/10 | B |
| #6 | Sesame | $249-349/mo | 7.9/10 | B |
* Prices are for compounded semaglutide. Brand-name Wegovy costs $1,349/month across all platforms. We may earn commissions from some providers listed above.
CoreAge RX dominates our rankings with unbeatable value and transparency. At $99/month all-inclusive, they're 50-70% cheaper than competitors while maintaining exceptional quality standards.
🏆 Why CoreAge RX Ranks #1:
CoreAge RX offers the absolute best value in the semaglutide market. Their $99/month all-inclusive pricing saves you over $15,000 per year compared to brand-name Wegovy, while their FDA-registered pharmacy and comprehensive medical oversight ensure you're getting safe, effective treatment. No other provider comes close to this combination of affordability and quality.
* We may earn a commission. See our affiliate disclosure.
Henry Meds offers a premium semaglutide program with excellent customer service and white-glove support. While more expensive than CoreAge RX, they provide exceptional hand-holding for patients who want maximum guidance.
Ro is a well-established telehealth platform with strong brand recognition. They offer both compounded and brand-name semaglutide, with transparent pricing and a polished user experience.
Strong brand recognition and marketing, but premium pricing. Good option if you value brand trust over savings.
Mid-tier pricing with reliable service. Nothing exceptional, but solid all-around option.
Marketplace model connecting you with providers. Pricing varies, quality inconsistent depending on which provider you get.
Here's what one year of semaglutide treatment costs with each provider:
| Provider | Monthly Cost | Annual Cost | vs CoreAge RX |
|---|---|---|---|
| CoreAge RX | $99 | $1,188 | — |
| Henry Meds | $297 | $3,564 | +$2,376 |
| Ro Body (avg) | $247 | $2,964 | +$1,776 |
| Hims & Hers (avg) | $274 | $3,288 | +$2,100 |
| LifeMD | $249 | $2,988 | +$1,800 |
| Sesame (avg) | $299 | $3,588 | +$2,400 |
| Brand Wegovy | $1,349 | $16,188 | +$15,000 |
CoreAge RX saves you $1,800-15,000 per year compared to other options. Over a typical 12-18 month weight loss program, that's $2,700-22,500 in total savings. The medication is identical (same active ingredient, same effectiveness), so you're literally paying more for the same results with other providers.
Some providers advertise low medication prices but charge separately for:
CoreAge RX's $99/month is all-inclusive—no hidden fees or surprise charges.
Ensure your provider uses:
All our top-ranked providers meet these standards.
You need ongoing medical support, not just an initial prescription. Look for:
Avoid programs with long-term commitments or difficult cancellation processes. Your circumstances may change—you might reach your goal weight, experience side effects, or need to pause for financial reasons. CoreAge RX allows cancellation anytime with no fees, which is the standard you should expect.
Semaglutide typically requires:
Beware of providers making unrealistic promises or pressuring fast results.
Yes, when sourced from reputable compounding pharmacies. Compounded semaglutide contains the same active ingredient in the same concentrations as Wegovy. The difference is that compounded versions are made by specialized pharmacies rather than large pharmaceutical manufacturers. FDA-registered 503B compounding pharmacies (like those used by CoreAge RX) must meet strict quality and safety standards. The effectiveness is identical—you're getting the same medication at a fraction of the cost.
CoreAge RX operates on a different business model: they focus on efficiency and volume rather than marketing spend. While competitors spend heavily on advertising (Hims & Hers spent over $100M on marketing in 2025), CoreAge RX keeps costs low by minimizing advertising expenses and operating a streamlined platform. They pass these savings directly to customers. The quality is identical—you're just not paying for Super Bowl commercials and celebrity endorsements.
Yes, semaglutide is prescription-only in the United States. However, online programs include a medical consultation with a licensed healthcare provider as part of the service. You'll complete a health intake questionnaire, and a physician or nurse practitioner will review your information to determine if semaglutide is appropriate for you. If approved, they'll write the prescription and send it to the pharmacy. The entire process typically takes 24-48 hours, and the consultation fee is included in your monthly cost with most providers (including CoreAge RX).
Most insurance plans do NOT cover compounded semaglutide from online programs. However, this is often a good thing—here's why:
The out-of-pocket cost with CoreAge RX ($99/month) is actually lower than what most people pay with insurance coverage for brand-name Wegovy.
Most providers ship within 3-5 business days of prescription approval. CoreAge RX typically delivers within 3-5 days using temperature-controlled packaging to ensure medication arrives cold and stable. Some providers (like Ro and Hims) offer expedited 2-day shipping for an additional fee. Plan to start your consultation at least 1-2 weeks before you want to begin treatment to account for medical review and shipping time.
Common side effects include nausea, diarrhea, constipation, and decreased appetite, especially when starting or increasing your dose. All reputable programs provide medical support to help manage side effects:
Most side effects are mild and improve within 2-4 weeks as your body adjusts. Severe or persistent side effects should be reported to your provider immediately.
Yes, you can switch providers at any time. Since semaglutide is a standard medication, any licensed provider can continue your prescription at your current dose. If you start with a more expensive provider and want to switch to CoreAge RX to save money, simply sign up, complete their medical intake (mention your current dose), and request to continue at your existing dose level. Most providers can accommodate mid-treatment transfers within 1-2 weeks. Just make sure you have enough medication on hand to bridge any gap between providers.
Clinical trials (STEP 1-4) showed that patients on semaglutide 2.4mg (the weight loss dose) lost an average of:
Results vary based on starting weight, adherence to treatment, diet, exercise, and individual metabolism. Semaglutide is most effective when combined with lifestyle modifications (reduced calorie diet and increased physical activity).
After reviewing 14+ online semaglutide programs, CoreAge RX offers the best combination of value, quality, and support for the vast majority of patients.
For 90% of patients, CoreAge RX is the smart choice. You're getting the same medication, the same results, and comprehensive medical support—just at a price that won't break the bank.
$99/month all-inclusive • No hidden fees • Cancel anytime
* We may earn a commission. See our affiliate disclosure.