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System Labs at a Glance
- What it is
- Sells a "compounded GLP-1/GIP" at $179 a month without telling you which drug it is
- Medication type
- Compounded only
- Medications offered
- Compounded "GLP-1/GIP" — active ingredient not named on the product page
- Sermorelin (injection and oral), NAD+ (injection and nasal spray), glutathione, MIC+B12, GHK-Cu cream — none of which are GLP-1s
- Pricing
- Compounded "GLP-1/GIP" at $179/mo, or $99 for a first month — supplies and cold-chain shipping included
- Insurance
- Cash-pay. Compounded medication and peptide therapies are never covered by insurance.
- Date reviewed
- August 7, 2026
How we scored it
Scores follow the published rubric in our provider comparison methodology.
Medical Disclaimer
We're not doctors, and this review is not medical advice. GLP-1 medications are prescription-only and require evaluation by a licensed healthcare provider. What works for one person may not work for another, and only a clinician who knows your history can determine whether a medication is appropriate for you. See our full medical disclaimer.
What Is System Labs?
System Labs is a telehealth platform built around peptides and longevity rather than weight loss. Founded in 2026 and based in San Francisco, its catalogue runs to NAD+ injections and nasal spray, sermorelin in injectable and oral forms, glutathione, MIC+B12 and a GHK-Cu cream, with a compounded GLP-1 alongside them. Intake is online, no appointment is required, and licensed clinicians review and approve prescriptions.
The GLP-1 product is $179/month, or $99 for a first month, including injection supplies, ongoing support and — genuinely worth noting — free two-day temperature-controlled shipping. GLP-1s require refrigeration, cold-chain failures appear in the complaint records of several competitors, and System Labs is one of very few providers that says anything about temperature control at all.
The problem is what it will not say. The product is marketed as "Compounded GLP-1/GIP", and the page does not disclose the active ingredient. A dual GLP-1/GIP agonist describes tirzepatide, so that is the reasonable inference — but an inference is not a disclosure. You cannot meaningfully consent to injecting a prescription medication whose name you have not been told, you cannot check it against your other medications, and you cannot look up its contraindications. Every serious provider in this comparison names the molecule.
System Labs is also very new, which cuts both ways. There is no meaningful independent record — no established BBB profile or review history to consult — so there is nothing to reassure you and nothing to warn you either.
How the Program Works
- Consultation process
- Online intake form with no appointment required, reviewed by licensed clinicians who approve and guide the treatment plan. System Labs offers 20% off a Rythm blood test alongside the GLP-1 plan rather than requiring lab work.
- Eligibility
- Clinician-assessed from the online intake. System Labs does not publish a BMI threshold or a list of states it serves.
- Provider involvement
- Licensed clinicians review intakes, approve prescriptions and provide ongoing support. System Labs does not name a medical director.
- Lab requirements
- Not required. A blood test is offered at a 20% discount as an add-on rather than as a condition of treatment.
- Pharmacy fulfillment
- Compounded by what System Labs describes as certified or licensed US pharmacies. It does not name them, and it does not name the active ingredient in its GLP-1 product either.
- Shipping frequency
- Free two-day temperature-controlled shipping, with injection supplies included. The explicit cold-chain handling is better than most competitors offer.
- Support services
- Ongoing support from what the company calls its care team, included in the monthly price.
System Labs Pricing
- Membership fee
- None stated. The monthly price covers the medication, injection supplies, shipping and ongoing clinician support.
- Medication fee
- The compounded GLP-1/GIP product is priced at $179/month with a $99 first-month rate. Other products are priced separately: NAD+ injection $149/month ($89 first month), NAD+ nasal spray $119/month ($69 first), glutathione injection $149/month ($79 first), sermorelin injection $219/month ($109 first), oral compounded sermorelin $159/month ($79 first), and MIC+B12 at $89/month.
- Cancellation policy
- System Labs states you can "pause or cancel anytime". It does not publish notice requirements or the mechanics of cancelling, so confirm both before subscribing.
- Refund policy
- Not published. Compounded medication is not returnable once dispensed.
- Insurance
- Cash-pay. Compounded medication and peptide therapies are never covered by insurance.
- HSA / FSA
- Not published. Confirm with your plan administrator.
Pricing details worth knowing
- The $99 is a first-month rate. Budget $179/month as the standing price.
- The GLP-1 product is not identified by molecule anywhere on the page. "GLP-1/GIP" describes the drug class of tirzepatide, but System Labs does not confirm that, and you should not have to infer it.
- Free two-day temperature-controlled shipping is a genuine differentiator — GLP-1s need refrigeration and most providers say nothing about cold chain.
- Injection supplies are included, which not every provider does.
- Most of the catalogue is peptides rather than GLP-1s. Sermorelin, NAD+, glutathione and MIC+B12 are not weight-loss medications and should not be assumed to work like one.
Prices change. Every figure above was taken from System Labs's published pages or the named sources at the bottom of this review, as of August 7, 2026. Telehealth pricing in this market changes frequently, and promotional rates expire. Confirm your actual cost at checkout before enrolling.
Pros and Cons
Pros
- Free two-day temperature-controlled shipping — one of very few providers to address the cold chain explicitly
- Injection supplies included in the monthly price
- $179/month with no separate membership fee, and a $99 first month
- Carries a clear FDA disclaimer stating that the peptide medications have not been approved by the FDA
- Licensed clinician review with no appointment required, and an optional discounted blood test
Cons
- Does not name the active ingredient in its GLP-1 product — the single most important disclosure there is
- Does not name its compounding pharmacy or publish a list of states served
- Founded in 2026, with no meaningful independent complaint or review record to consult
- No published refund policy and no detail on how cancellation works
- The $99 is a first-month rate, not the ongoing price
- Most of the catalogue is peptides with far weaker evidence than GLP-1s
Who System Labs May Be Best For
People already buying peptides who want a GLP-1 from the same platform and will ask which molecule it is before starting
Anyone who has had a medication arrive warm elsewhere and wants explicit temperature-controlled shipping
Limitations
Ask which drug it is, in writing, before you pay. If a provider will not name the active ingredient in a prescription medication, that alone is a reason to go elsewhere.
Check the answer against your own contraindications and other medications. You cannot do that for an unnamed drug.
There is no track record here. A company founded in 2026 has no complaint history — which is not the same as a clean one.
Peptides such as sermorelin, NAD+ and glutathione are not weight-loss treatments and have substantially weaker evidence than GLP-1 medications. Do not read the GLP-1 evidence across to them.
About Compounded GLP-1s
The FDA declared the tirzepatide shortage resolved in December 2024 and the semaglutide shortage resolved in February 2025, which ended the window for compounding pharmacies to make large volumes of copies of those drugs (503A pharmacies had until April 22, 2025; 503B outsourcing facilities until May 22, 2025). Many telehealth companies continue to offer compounded GLP-1s prescribed for an individual patient — often as a personalized dose, a microdose, or a formulation combined with a vitamin such as B12 or B6. That practice sits in a contested legal area, and the FDA has continued to act. In a Federal Register notice published on May 1, 2026, the FDA proposed not to include semaglutide, tirzepatide or liraglutide on the 503B bulks list, saying it had not identified sufficient evidence of a clinical need for outsourcing facilities to compound them from bulk substances; the comment period was extended to July 30, 2026. Separately, in February 2026 the FDA issued warning letters to 30 telehealth companies over false or misleading claims about compounded GLP-1s, and it has continued: a further round dated 8 June 2026 — 25 warning letters, posted publicly on 16 June 2026 — reached companies including Medica Weight Loss, FITISH and Roen Health (RoenRx), again over false or misleading claims about compounded semaglutide and tirzepatide that the FDA said made the products misbranded under sections 502(a) and 502(bb) of the FD&C Act. The claims cited included suggesting the products were FDA-approved, implying equivalence to Ozempic, Wegovy, Mounjaro or Zepbound, and asserting the "same active ingredient" or "same results" as the approved drugs. Compounded medications are not FDA-approved, which means they have not gone through the same review as the brand-name products.
None of that is specific to System Labs — it applies to every provider offering compounded medication. We cover the trade-offs in detail in our guide to brand-name versus compounded GLP-1s.
Alternatives to System Labs
Trimi
Names the molecule, both compounding pharmacies and a licence number, at $99/mo
Read review →Embody
Names four compounding pharmacies and identifies its medications plainly
Read review →NovoCare Pharmacy
FDA-approved Wegovy at $149/mo — you know exactly what you are getting
Read review →vs. CoreAge RX, our top-rated platform
Across the platforms we've reviewed, CoreAge RX remains our highest-rated option for cash-pay patients, with compounded semaglutide from $99/month and tirzepatide from $149/month including free two-day shipping. Whether it beats System Labs for you depends on the things this review has covered — insurance, medication type, and how much support you actually want.
Frequently Asked Questions
What medication is System Labs actually selling?
It does not say. The product is marketed as "Compounded GLP-1/GIP" and the page does not disclose the active ingredient. A dual GLP-1/GIP receptor agonist is the drug class tirzepatide belongs to, so that is the obvious inference — but System Labs does not confirm it, and you should not have to guess. Ask before you pay, get the answer in writing, and treat an unwillingness to name it as disqualifying.
How much does System Labs cost?
The compounded GLP-1 product is $179/month, with a $99 rate for the first month. That covers the medication, injection supplies, free two-day temperature-controlled shipping and ongoing clinician support, with no separate membership fee. Its other products are priced individually — NAD+ injection at $149/month, sermorelin injection at $219/month, glutathione at $149/month and MIC+B12 at $89/month, each with a discounted first month.
Is temperature-controlled shipping actually important?
Yes, and it is underrated. GLP-1 medications require refrigeration, and cold-chain failures — packages left in heat, or arriving with warm ice packs — appear in the complaint records of multiple providers we have reviewed. Most providers say nothing about how they ship. System Labs advertising two-day temperature-controlled shipping with supplies included is a real advantage, and one of the better reasons to consider it.
Are sermorelin, NAD+ and glutathione weight-loss treatments?
No. Sermorelin is a growth-hormone secretagogue, NAD+ is marketed for energy and healthy ageing, and glutathione is an antioxidant. None is a GLP-1 and none should be expected to produce weight loss the way semaglutide or tirzepatide does. These are compounded peptide therapies which, as System Labs itself discloses, have not been approved by the FDA. The evidence base behind them is considerably weaker than that behind GLP-1 medications.
Is System Labs legitimate?
It appears to be an operating telehealth company using licensed clinicians and US compounding pharmacies, and it discloses plainly that its peptide medications are not FDA-approved. But it was founded in 2026 and has no established independent review or complaint record, so there is very little to verify it against — and its refusal to name the active ingredient in a prescription product it sells is a serious mark against it regardless of anything else.
Who should not use System Labs?
Anyone who wants to know what they are taking, which should be everyone. Anyone who wants an established track record, or a published refund policy. Separately, GLP-1 medications are not appropriate if you have a personal or family history of medullary thyroid carcinoma or MEN 2, if you are pregnant or trying to conceive, or if you have had pancreatitis — and you cannot properly check contraindications against a medication that has not been named. Common side effects include nausea, vomiting, diarrhoea and constipation. A licensed clinician who knows your history should make that assessment.
The Verdict
System Labs is a San Francisco peptide and longevity telehealth platform founded in 2026, selling NAD+, sermorelin, glutathione and a compounded GLP-1 at $179/month, $99 for a first month. Its temperature-controlled shipping is a real point in its favour. But it markets the weight-loss product as "compounded GLP-1/GIP" without naming the active ingredient, which is the one thing you need to know before injecting something.
Opens System Labs's official site · Verify current pricing there
Compare Every Provider Side by Side
See how System Labs stacks up against every platform we've reviewed on price, medication type, and what's actually included.
How We Researched This Review
We compiled this review on August 7, 2026 from System Labs's own published pages plus independent reporting. We have not signed up for this service ourselves, and we say so rather than implying firsthand testing. Where System Labs does not publish a detail — refund terms, lab requirements, pharmacy partners — we've said that plainly instead of guessing.
Sources
- systemlabs.com/lander/glp-1 — "Compounded GLP-1/GIP" at $179/month with a $99 first month, injection supplies included, 20% off a Rythm blood test, free two-day temperature-controlled shipping, "pause or cancel anytime", and no disclosure of the active ingredient (checked August 7, 2026)
- systemlabs.com — NAD+ injection $149/mo ($89 first), NAD+ nasal spray $119/mo ($69 first), glutathione injection $149/mo ($79 first), sermorelin injection $219/mo ($109 first), oral compounded sermorelin $159/mo ($79 first), MIC+B12 $89/mo; "compounded by a certified U.S. pharmacy"; no named pharmacy, medical director or state list
- systemlabs.com FDA disclaimer — "The peptide medications...have not been approved by the FDA."
- Company profile reporting: founded 2026, headquartered in San Francisco, California
- No established BBB profile or substantial Trustpilot history was locatable for System Labs, consistent with a company founded in 2026 (checked August 7, 2026)
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