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Success by Sesame at a Glance
- What it is
- Marketplace pricing with an all-inclusive option and a Costco partnership
- Medication type
- Brand-name and compounded
- Medications offered
- Compounded semaglutide
- Brand-name GLP-1s including Wegovy (injection and pill), Ozempic, Zepbound
- Pricing
- Subscription from $59/mo annually or $99/mo; all-inclusive option $249/mo
- Insurance
- Sesame is a cash-pay marketplace by design — it is built for people without coverage or with coverage that will not pay for weight management. Brand-name prescriptions written through Sesame can still be run through your own insurance at the pharmacy.
- Date reviewed
- August 5, 2026
How we scored it
Scores follow the published rubric in our provider comparison methodology.
Medical Disclaimer
We're not doctors, and this review is not medical advice. GLP-1 medications are prescription-only and require evaluation by a licensed healthcare provider. What works for one person may not work for another, and only a clinician who knows your history can determine whether a medication is appropriate for you. See our full medical disclaimer.
What Is Success by Sesame?
Sesame is a cash-pay marketplace first and a weight program second. That shows up in the pricing: it publishes visit prices, subscription prices, and medication prices as separate line items rather than a single bundled number.
Two paths matter here. A lower subscription that covers clinical care while you source medication separately, and an all-inclusive option that includes compounded medication in one monthly price.
The Costco partnership is a genuine differentiator. Costco members get discounted Sesame pricing, and the initial three-month weight-loss subscription is published at $179.
How the Program Works
- Consultation process
- Video visits with licensed clinicians booked through the Sesame marketplace, plus unlimited chat on the subscription.
- Eligibility
- Clinician-assessed at the visit. Sesame supports both people seeking brand-name prescriptions and people seeking compounded options.
- Provider involvement
- Board-certified clinicians conduct the visits and prescribe. Sesame emphasizes that clinical oversight is included in the program price.
- Lab requirements
- Sesame includes labs in its published weight-loss program description, which is unusual — most competitors leave labs to the clinician's discretion.
- Pharmacy fulfillment
- Brand-name prescriptions go to a pharmacy of your choice or a manufacturer pharmacy; the all-inclusive program includes compounded medication from partner pharmacies.
- Shipping frequency
- Depends on the path chosen. Billing on the subscription runs on a 28-day cycle per third-party reporting.
- Support services
- Video visits, labs, unlimited chat with the care team, and marketplace access to other cash-pay services at member rates.
Success by Sesame Pricing
- Membership fee
- Sesame publishes the Success by Sesame subscription starting at $59/mo with an annual subscription, and the program "starting at just $99/mo" on its main service page.
- Medication fee
- Not included on the subscription-only path. The all-inclusive option, reported at $249/month, includes compounded medication and clinical oversight.
- Cancellation policy
- Subscriptions renew on their stated cycle; annual subscriptions are the cheapest per month and the largest commitment. Cancel before renewal to avoid the next cycle.
- Refund policy
- Sesame does not publish a blanket refund policy for the weight program.
- Insurance
- Sesame is a cash-pay marketplace by design — it is built for people without coverage or with coverage that will not pay for weight management. Brand-name prescriptions written through Sesame can still be run through your own insurance at the pharmacy.
- HSA / FSA
- Sesame is widely used with HSA/FSA cards for cash-pay visits. Confirm eligibility with your administrator.
Pricing details worth knowing
- Sesame publishes Wegovy pill pricing at $149/mo on its semaglutide page.
- Costco members: $29 virtual visits, $72 checkups, 10% off other Sesame services, and an initial three-month weight-loss subscription of $179.
- The subscription fee does not include medication unless you choose the all-inclusive option.
Prices change. Every figure above was taken from Success by Sesame's published pages or the named sources at the bottom of this review, as of August 5, 2026. Telehealth pricing in this market changes frequently, and promotional rates expire. Confirm your actual cost at checkout before enrolling.
Pros and Cons
Pros
- Publishes real prices for visits, subscriptions, and medication separately
- Both a cheap clinical-only path and an all-inclusive medication path
- Labs included in the published program
- Costco member pricing is a real discount, not a token one
Cons
- The number of published price points ($59, $99, $249, $179 Costco) makes it genuinely confusing to work out your own total
- Cheapest rate requires an annual subscription
- Not a coaching-heavy program if that is what you want
Who Success by Sesame May Be Best For
Costco members
Cash-pay patients who want visits and labs included
People who want to compare an all-inclusive price against a build-your-own price
Limitations
Marketplace model means less continuity with a single clinician than a dedicated clinic
Pricing pages across Sesame and its partners quote different figures — verify at checkout
About Compounded GLP-1s
The FDA declared the tirzepatide shortage resolved in December 2024 and the semaglutide shortage resolved in February 2025, which ended the window for compounding pharmacies to make large volumes of copies of those drugs (503A pharmacies had until April 22, 2025; 503B outsourcing facilities until May 22, 2025). Many telehealth companies continue to offer compounded GLP-1s prescribed for an individual patient — often as a personalized dose, a microdose, or a formulation combined with a vitamin such as B12 or B6. That practice sits in a contested legal area, and the FDA has signaled further action. Compounded medications are not FDA-approved, which means they have not gone through the same review as the brand-name products.
None of that is specific to Success by Sesame — it applies to every provider offering compounded medication. We cover the trade-offs in detail in our guide to brand-name versus compounded GLP-1s.
Alternatives to Success by Sesame
PlushCare
Even cheaper membership if you have insurance for visits
Read review →Mochi Health
Simpler flat pricing without the marketplace complexity
Read review →Walgreens Virtual Healthcare
Per-visit pricing with no subscription at all
Read review →vs. CoreAge RX, our top-rated platform
Across the platforms we've reviewed, CoreAge RX remains our highest-rated option for cash-pay patients, with compounded semaglutide from $99/month and tirzepatide from $149/month including free two-day shipping. Whether it beats Success by Sesame for you depends on the things this review has covered — insurance, medication type, and how much support you actually want.
Frequently Asked Questions
How much does Success by Sesame cost?
Sesame publishes the subscription starting at $59/month with an annual subscription, and describes the program as starting at $99/month. An all-inclusive option that bundles compounded medication has been reported at $249/month. The subscription alone does not include medication.
What do Costco members get?
Costco members get discounted Sesame pricing — $29 virtual visits, $72 checkups, and 10% off other services — with the initial three-month weight-loss subscription published at $179.
Does Sesame include lab work?
Yes. Sesame's published weight-loss program description includes video visits, labs, and unlimited chat in the subscription, which is more than most competitors include.
The Verdict
Sesame runs a cash-pay healthcare marketplace, and Success by Sesame is its weight-loss program. It publishes both a subscription-only path and an all-inclusive path that bundles medication, plus discounted pricing for Costco members.
Opens Success by Sesame's official site · Verify current pricing there
Compare Every Provider Side by Side
See how Success by Sesame stacks up against every platform we've reviewed on price, medication type, and what's actually included.
How We Researched This Review
We compiled this review on August 5, 2026 from Success by Sesame's own published pages plus independent reporting. We have not signed up for this service ourselves, and we say so rather than implying firsthand testing. Where Success by Sesame does not publish a detail — refund terms, lab requirements, pharmacy partners — we've said that plainly instead of guessing.
Sources
- sesamecare.com/service/online-weight-loss-program (subscription pricing, labs, chat)
- sesamecare.com/blog/sesame-weight-loss-announcement (Costco pricing)
- fiercehealthcare.com and finance.yahoo.com (all-inclusive $249 program reporting)
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